- Metastatic Tumors are the most common malignancy encountered in the central nervous system
- Up to 30-40% of cancer patients develop brain metastases at some point
- Conventional therapeutic options include surgical resection, stereotactic radiosurgery and whole brain radiotherapy
- Lung, breast and melanoma are the 3 most common primary tumors that metastasize to the brain
- Many brain metastases can be cured or controlled with a combination of surgical resection and stereotactic radiosurgery
- Suboptimal treatment impairs quality of life and survival
- Treatment
- Multimodality treatment is often necessary
- Combination of surgical resection, stereotactic radiosurgery and whole brain radiotherapy
- Chemotherapy has limited role in the management of brain metastases. Response rate less than 5%
Metastatic Tumors
