Board-certified neurosurgeon specializing in cranial, spinal, and endovascular procedures — performing the majority of stereotactic radiosurgery cases at Long Island Brain & Spine.
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80+
Peer-reviewed publications
20+
Years specialized training
3
Long Island locations
FAANS
Board Certified
Affiliated with
The only Joint Commission Certified Comprehensive Stroke Center on Long Island’s South Shore.
Areas of Expertise
A full spectrum of brain, spine, and cerebrovascular care.
Dr. Missios provides comprehensive neurosurgical care across brain surgery, spine surgery, stereotactic radiosurgery, and endovascular techniques — offering patients a full range of treatment options from a single practice.
Brain Surgery
Complex cranial procedures including benign and malignant tumor resection, aneurysm clipping, hydrocephalus treatment, and advanced intraoperative neuronavigation — led by Dr. Missios as Director of Brain Tumor Surgery at Good Samaritan.
Brain conditions →Spine Surgery
Treatment for degenerative, traumatic, and tumor-related spinal conditions — including minimally invasive approaches for herniated discs, stenosis, and spondylolisthesis.
Spine conditions →Stereotactic Radiosurgery
Precise, non-invasive radiation treatment for brain tumors, metastases, AVMs, and trigeminal neuralgia — delivered on Long Island's advanced HyperArc platform.
Explore SRS →Endovascular Neurosurgery
Minimally invasive treatment of stroke, brain aneurysms, and vascular malformations — at the South Shore's only Joint Commission Certified Comprehensive Stroke Center.
Stroke & vascular →✦ Stereotactic Radiosurgery Program
One of New York’s most advanced radiosurgery programs — on Long Island’s South Shore.
Stereotactic radiosurgery (SRS) delivers precisely focused radiation to tumors and lesions without a surgical incision — often in a single session. Good Samaritan University Hospital’s program uses the Varian Edge system with HyperArc, a platform chosen specifically to compete with Gamma Knife and CyberKnife centers at larger academic health systems.
“We’ve treated patients with as many as 15 metastatic brain lesions in a single 20-minute session. The precision is excellent, and patients don’t need to be placed in a frame.”
— Dr. Missios, quoted in Varian Medical Systems case study
SRS is highly effective for brain tumors, metastases, arteriovenous malformations, trigeminal neuralgia, acoustic neuromas, and meningiomas — often as a primary treatment or as follow-up after open surgery.
The multidisciplinary team
Symeon Missios, MD, FAANS
Neurosurgeon — target identification, contouring, and surgical planning. Fellowship-trained at Cleveland Clinic in Neurosurgical Oncology and SRS.
Johnny Kao, MD
Chair of Radiation Oncology and Director of the Cancer Institute at Good Samaritan — Castle Connolly Top Doctor.
Vikram Soni, MD
Radiation Oncologist, fellowship-trained at Baylor College of Medicine.
Technology
Varian Edge® with HyperArc + TrueBeam® at the Cancer Institute at Good Samaritan
Education & Training
Dual subspecialty fellowships.
Board certified since 2014.
Training across the top academic programs in neurosurgical oncology, stereotactic radiosurgery, and endovascular neurosurgery — with a research output to match.
About Dr. Missios
Providing Excellence in Neurosurgery.
Dr. Missios is a board-certified neurosurgeon specializing in both cranial and spinal procedures, with dual subspecialty fellowships in Neurosurgical Oncology & Stereotactic Radiosurgery (Cleveland Clinic) and Endovascular Neurosurgery & Neurovascular Critical Care (Thomas Jefferson University).
His clinical expertise spans complex brain tumor resection using intraoperative tractography and brain mapping, minimally invasive endovascular treatment of stroke and aneurysms, and stereotactic radiosurgery — a non-invasive alternative to open surgery for many intracranial conditions.
Beyond clinical practice, Dr. Missios has co-authored more than 80 peer-reviewed publications and serves as a reviewer for multiple neurosurgical journals. He is a member of the Population Health Research Institute of New York and has received first-place recognition at the American Association of Neurological Surgeons annual meeting.
Patient Stories
Care that families remember.
From life-saving emergency interventions to thoughtful long-term recovery, the stories patients and families share speak to what it means to receive care from Dr. Missios.
“Within an hour, my nephew was in the operating room.”
On the night of the accident, when my nephew’s epidural hematoma began to expand, Dr. Missios was at the bedside immediately. His ability to explain the urgency of the situation with both clarity and compassion was remarkable. His surgical skill saved my nephew’s life, and his personal phone call to me immediately following the procedure provided our family with the reassurance we so desperately needed.
“My husband has made a full recovery after suffering a major stroke.”
The rapid, skillful and compassionate response by you and your team is a gift for which my family and I are forever grateful.
— Linda & Robert M.
“The only one to help me through the process.”
Thank you for your care and concern throughout my attempt for the nerve stimulator surgeries. You were the only one to help me through the process.
— Cindy C.
Where to find us
Three locations across Long Island.
Convenient access from the South Shore to the North Shore, with consultations, imaging, and surgical coordination handled through a single unified team.
Location 01
West Islip
Long Island Brain & Spine
380 Montauk Highway
West Islip, NY 11795
Location 02
Smithtown
St. Catherine of Siena Medical Building
48 Route 25A, Suite 302
Smithtown, NY 11787
Location 03
West Islip
The Cancer Institute at Good Samaritan
111 Beach Drive
West Islip, NY 11795
Request a Consultation
Take the first step toward answers.
Whether you’re facing a new diagnosis, seeking a second opinion, or have been referred for specialist care — we’ll get you an appointment quickly and walk you through every step.
or toll-free (888) 737-5427